Injections with "dermal fillers" containing hyaluronic acid appear to stimulate production of collagen, a primary protein in the skin. This means that dermal fillers may actually restore the structure of sun-damaged skin, according to an article in the February issue of Archives of Dermatology. Injectable skin fillers have become increasingly popular for correcting the lines and wrinkles associated with aging, as well as acne scars and other skin conditions. Hyaluronic acid, a compound that occurs naturally in the skin and connective tissue, is among the most widely used fillers in the United States. Its molecules bind to water in the skin, hydrating and firming its structure, and the loss of hyaluronic acid with aging is associated with skin dehydration and wrinkling. .

Interview : Michael Bay

I know my colleagues are going to have Transformers'' questions, but I wanted to know your reaction to 'Hot Fuzz' which was so inspired by 'Bad Boys 2', and that you said that you were offered 'Die Hard 4' and I was wondering if this hadn't come together would you have considered doing that?

MB: Die Hard 4, no, I don't think so. Hot Fuzz, I haven't seen it yet, because I was finishing this movie. It's really hard, the end of your post schedule is such a grind, seeing a movie is like the last thing you want to do when you go home. I thought this would be an easy post, on our budget we had a hiatus scheduled in here, because I said, "Oh, my God, I have the longest post schedule," I didn't think the robots would be that hard, but I was directing them all the way to the very end.

Isolagen Inc. Completes Injections Of Isolagen Therapy(TM) In Phase ...

Isolagen(TM), Inc. (Amex: ILE) announced that injections have been completed in the pivotal Phase III multi-center, double-blind, randomized, placebo-controlled clinical trials evaluating the Isolagen Therapy(TM) for the treatment of nasolabial folds, or wrinkles (Studies IT-A-005 and IT-A-006). Subjects have advanced to the follow-up period of the study.

Isolagen also announced the completion of injections in the Phase II open label study designed to gather further safety and potential application information on the use of the Isolagen Therapy(TM) for the full face (Study IT-A-007). The subjects in this study also have advanced to the follow-up period.

"These are important clinical milestones to Isolagen, especially the advancement of our lead Phase III pivotal wrinkle study to the follow-up period of the trial," said Declan Daly, Chief Executive Officer of Isolagen, Inc.